HLA Antibodies in ATGs
نویسندگان
چکیده
منابع مشابه
Anti-hla Antibodies Detection Techniques
Kidney transplantation is now accepted to be the best treatment for patients with end-stage renal disease, conferring an increased survival and a better quality of life compared to dialysis [1-2]. There has been an improvement in allograft survival in the last decades [3-4] and mostly in the short-term outcomes, in part because we have a better understanding and a better control of the cellular...
متن کاملJournal Watch Non-HLA antibodies
The clinical impact of non-HLA specific antibodies either alone or in concert with donor HLA specific antibodies (DSA) has been an intense area of research in kidney transplantation and more recently in thoracic transplantation as well. These non-HLA antigens include receptors expressed by the vascular endothelium such as the G protein coupled receptors (GPCRs), Major Histocompatibility Complex...
متن کاملAnti-HLA Antibodies and Kidney Allograft Outcomes in Recipients with Donor Bone Marrow Cell Infusion
Background: Anti-HLA-antibodies are known to affect the allograft survival in transplant recipient patients. Objective: The aim of this study was to evaluate the association between anti-HLA antibodies and kidney allograft outcomes, particularly in recipients with concur-rent donor bone marrow cell infusion (DBMI). Methods: Between June 2006 and May 2007, forty living unrelated donor kidney tra...
متن کاملAntipeptide antibodies: do they distinguish HLA-alloantigens?
Three immune sera, raised in rabbits against synthetic peptides corresponding in sequence to predetermined regions of the HLA-DQ histocompatibility antigens, were tested for their ability to recognize phenotypically distinct human lymphoblastoid cell lines. The immune sera readily recognize the immunogen. When tested on the cells, they react poorly but seem to exhibit a certain degree of specif...
متن کاملThe role of platelet microparticles in the production of antibodies from B lymphocytes against HLA-DR antigen in vitro
Background: Platelets can activate B cells and stimulate them for the production of antibodies. Since platelet microparticles (PMPs) originate from platelets, they may have the same virtue. In the present study, the effect of PMPs was investigated on the production of human leukocyte antigen (HLA)-specific antibody from B cells in vitro. Materials and Methods: In this experimental study, HLA-D...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2014
ISSN: 1600-6135
DOI: 10.1111/ajt.12621